Miltefosine Powder CAS No 58066-85-6

Active Pharmaceutical Ingredients CDP-choline (sc-200713) and phosphatidylethanolamine which interferes with biosynthesis of phosphatidylcholine. Furthermore, data suggests that this compound can slow down the formation of sphingomyelin, which promotes intracellular accumulation of ceramide. Miltefosine is an inhibitor of CCT and PKC, Medicine Raw Material.

Miltefosine Powder CAS No 58066-85-6

[Product Name]: Miltefosine
[Apperance]: White Powder

[Specification]: 99%

[Test Method]: HPLC
[Storage]: Store in a cool, dry place and sealed container.

1. Miltefosine is a phospholipid drug. Chemically it is a derivative of alkylphosphocholine compounds discovered in the early 1980s. It was developed in the late 1980s as an anticancer drug. Simultaneously but independently it was found that the drug could kill Leishmania parasites, and since the mid-1990s successful clinical trials were conducted. The drug became the first (and still the only prescribed) oral drug in the treatment of leishmaniasis. 
2. It is now known to be a broad-spectrum antimicrobial drug, active against pathogenic bacteria and fungi, as well as humantrematode Schistosoma mansoni. 
3. Miltefosine is usedfor the treatment of visceral and cutaneous leishmaniasis, and is undergoing clinical trialsfor this use in several other countries, such as Brazil and Guatemala. Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis.

Anti-Cancer Ingredients Mittifosin is an anti-cancer chemical that enters the cell membrane and blocks cellular signaling processes to induce a specific functional disorder that prevents further tumor growth. Palliative treatment of breast cancer skin that is difficult to treat with conventional treatment.

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